Lisinopril

Lisinopril is an ACE inhibitor. ACE stands for angiotensin converting enzyme.

Usage

Side effects

Pharmacology

Mechanism of action

Competitive inhibitor of angiotensin-converting enzyme (ACE); prevents conversion of angiotensin I to angiotensin II, a potent vasoconstrictor; results in lower levels of angiotensin II which causes an increase in plasma renin activity and a reduction in aldosterone secretion; a CNS mechanism may also be involved in hypotensive effect as angiotensin II increases adrenergic outflow from CNS; vasoactive kallikreins may be decreased in conversion to active hormones by ACE inhibitors, thus reducing blood pressure

Half-Life Elimination

12 hours

Drugs: Lisinopril