Valsartan is an ACE inhibitor. ACE stands for angiotensin converting enzyme.


Side effects


Mechanism of action

Valsartan produces direct antagonism of the angiotensin II (AT2) receptors, unlike the ACE inhibitors. It displaces angiotensin II from the AT1 receptor and produces its blood pressure-lowering effects by antagonizing AT1-induced vasoconstriction, aldosterone release, catecholamine release, arginine vasopressin release, water intake, and hypertrophic responses. This action results in more efficient blockade of the cardiovascular effects of angiotensin II and fewer side effects than the ACE inhibitors.

Half-Life Elimination

~6 hours; ~35% longer in elderly patients

Drugs: Valsartan